Cyclobenzaprine is structurally similar to tricyclic antidepressants like amitriptyline and cyproheptadine. It is a centrally acting skeletal muscle relaxant which relieves skeletal muscle spasms of local origin without interfering with muscle function. Cyclobenzaprine is FDA approved as an adjunct to rest for the treatment of muscle spasms associated with acute, painful musculoskeletal conditions. It's exact mechanism is 5-HT2 receptor antagonist which is responsible for the antispasmodic effect, due to inhibition of serotonergic, not noradrenergic, descending systems in the spinal cord. Synthesis Structurally similar drugs with MOA Other marketed muscle relaxants Reference NIH National library of medicine WO 2012/098563/A2
SUFFIX and PREFIX The presence of a characteristic (or functional) group is denoted by a prefix or suffix attached to the parent name The most senior one, the principal characteristic group, is cited as the suffix, while all other groups are cited as prefixes. For nomenclature purpose, C-C multiple bonds are not considered to be characteristic groups Seniority order for characteristic groups Examples Reference Brief guide to the nomenclature of organic chemistry, Pure Appl. Chem., 2020, 92(3), 527-536