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Cyclobenzaprine

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Cyclobenzaprine is structurally similar to tricyclic antidepressants like amitriptyline and cyproheptadine. It is a centrally acting skeletal muscle relaxant which relieves skeletal muscle spasms of local origin without interfering with muscle function. Cyclobenzaprine is FDA approved as an adjunct to rest for the treatment of muscle spasms associated with acute, painful musculoskeletal conditions. It's exact mechanism is 5-HT2 receptor antagonist which is responsible for the antispasmodic effect, due to inhibition of serotonergic, not noradrenergic, descending systems in the spinal cord. Synthesis Structurally similar drugs with MOA Other marketed muscle relaxants Reference NIH National library of medicine WO 2012/098563/A2

Characteristic groups - Suffixes and Prefixes

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 SUFFIX and PREFIX The presence of a characteristic (or functional) group is denoted by a prefix or suffix attached to the parent name The most senior one, the principal characteristic group, is cited as the suffix, while all other groups are cited as prefixes. For nomenclature purpose, C-C multiple bonds are not considered to be characteristic groups Seniority order for characteristic groups Examples Reference Brief guide to the nomenclature of organic chemistry, Pure Appl. Chem., 2020, 92(3), 527-536 

Nomenclature

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IUPAC - International Union of Pure and Applied Chemistry, which provides recommendations on many aspects of nomenclature. Nomenclature is a key tool for effective communication in the chemical sciences. There are 3 types of chemical nomenclature Nomenclature of Organic chemistry - Blue book Nomenclature of Inorganic chemistry - Red book Nomenclature of Polymer chemistry - Purple book Substitutive Nomenclature It is the main method for organic-chemical compounds. It is used mainly for compounds of carbon and elements of groups 13 - 17. For naming purposes, a chemical compound is treated as a combination of a parent compound and characteristic (functional) groups, one of which is designated the principal characteristic group A systematic name is based on the name of most senior parent compound in which the substitution of hydrogen atoms is represented by a SUFFIX for the principal characteristic group(s). PREFIXes representing less senior characteristic groups and other substituent gro